CBD, HEALTH

CBD Industry News

CBD industry news

CBD Industry News

Since almost the dawn of written history, humans have grown and consumed the female cannabis plant’s flowering tops, also known as marijuana. According to data in the book “Marihuana: The First Twelve Thousand Years,” cannabis use dates back as long as 12,000 years, making the plant one of humanity’s oldest crops. Today, cannabis and other cannabinoid substances are frequently used to treat symptoms of ailments or reduce pain. There are more than 100 distinct cannabinoids in marijuana plants. Each one affects the body uniquely. The major substances found in cannabis that are used in medicine are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is also responsible for the “high” that results from marijuana consumption or smoking. As clinical research into cannabinoids’ medicinal efficacy has expanded, so has researchers’ awareness of cannabis’ unique ability to treat disease. Scientists today are investigating the possible role of cannabinoids to modulate disease, whereas researchers in the 1970s, 1980s, and 1990s mainly evaluated marijuana’s capacity to temporarily alleviate various disease symptoms, such as nausea connected with cancer chemotherapy. Today, researchers for the CBD industry news are looking into the potential of cannabinoids to treat neurological conditions like Alzheimer’s disease and amyotrophic lateral sclerosis (also known as Lou Gehrig’s disease) as well as autoimmune diseases like multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease. In the CBD industry news, cannabis is also being studied for its anti-cancer properties since a growing body of preclinical data suggests that cannabinoids can prevent the spread of particular cancer cells through apoptosis (programmed cell death) and angiogenesis inhibition (the formation of new blood vessels). Cannabis use as an alternative for many patients seeking harm reduction is also being studied by researchers. Numerous studies, in the CBD industry news area, have examined individuals’ usage of cannabis as an alternative to other prescription medications, including opioids.

In comparison to what many CBD industry news researchers could have predicted 30 or even 20 years ago, it can be argued that these recent discoveries reflect much larger and more substantial applications for cannabis treatments in the current times. 

Current Trends in CBD Industry News

  1. CBD and the fight against COVID-19: It was a happy accident that the theory to investigate CBD as a possible COVID-19 treatment germinated. Because of the anti-inflammatory properties of CBD, researchers hypothesized that it would prevent the so-called ‘cytokine storm,’ the second stage of COVID infection that involves the immune system. Surprisingly, it directly prevented viral multiplication in lung cells, according to a study, published on January 20, 2022, in Science Advances (1). The study demonstrated that the ability of SARS-CoV-2 to enter the cell was unaffected by CBD. Instead, early in the infection cycle and six hours after the virus had already invaded the cell, CBD was efficient at preventing replication. Further research revealed that, in addition to the initial strain of SARS-CoV-2, CBD also had the same effects on three different strains of SARS-CoV-2 and two additional cell types. The researchers demonstrated that CBD inhibits SARS-CoV-2 replication by activating one of the host cell stress responses and causing the production of interferons, an antiviral cell protein. Although the study’s findings are intriguing, more research is required to establish the specific CBD dosage that prevents SARS-CoV-2 infection in humans, as well as the drug’s safety profile and any potential side effects. We do not recommend you rely on CBD to combat COVID-19 and it’s important to recognize that this was only one study and we need more research on this topic. Always talk to your healthcare provider and seek professional guidance. 
  1. CBD for pets: When individuals first acknowledged the therapeutic benefits of CBD, many questioned whether it would also benefit their pets including dogs and cats. Despite recent increases in the usage of cannabis medicines to treat domestic animals’ behavioral issues, there is a dearth of clinical trial literature to assess the efficacy of these products (2, 3). Veterinary professionals often feel uncomfortable suggesting cannabis-derived treatments to pet owners, yet CBD is steadily growing in importance as a tool for the treatment of pain, inflammation, seizures, and anxiety. In a recent study in the CBD industry news, CBD oil was given to shelter dogs for 45 days while being monitored for aggressive behavior toward their human handlers (4). None of the dogs in the CBD treatment group showed any negative side effects and all tolerated CBD well. It suggests a potential new therapeutic purpose for CBD for our cherished pets, albeit the study’s tiny sample size. These advantages of CBD are likely to be valued by many dedicated volunteers, veterinarians, and staff members of animal shelters. In another study, cats responded better than dogs to cannabis medication for treating anxiety. Like dogs, cats also experienced reductions in the pain associated with ailments like arthritis. Even while research on cats is still less developed than that on dogs, top cannabis scientists intend to start focusing their attention on the subject.
  1. Cannabis’s Effects on the Aging Adult Brain: Age-related memory loss and cognitive decline are influenced by changes in the strength of communication among various brain regions. Researchers in Colorado employed functional neuroimaging to see how regular cannabis usage (at least once per week) changed the strength of connectivity across multiple brain regions, which generally declines with age (5). In contrast to older persons who did not use cannabis, it was found that older cannabis users exhibited stronger communication patterns between the hippocampus, the parahippocampal gyrus, and the cerebellum. The higher connection among older cannabis users was comparable to that of considerably younger non-using adults, which raises the possibility that cannabis usage may help prevent some of the cognitive impairments associated with aging. Because it wasn’t a randomized, controlled experiment, these findings are not causal, but they offer some of the first human data to support findings from rodent research showing that frequent use of tiny quantities of cannabis prevented age-related brain alterations and cognitive decline. 

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This article was written by Dr. Peace Lily Scientific Communications Intern, Jahnabi Saikia, and edited by Dr. Najifa Choudhury, PharmD.

References:

  1. Nguyen LC, Yang D, Nicolaescu V, et al. Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response. Preprint. bioRxiv. 2021;2021.03.10.432967. Published 2021 Mar 10. doi:10.1101/2021.03.10.432967
  2. De Briyne N, Holmes D, Sandler I, et al. Cannabis, Cannabidiol Oils and Tetrahydrocannabinol-What Do Veterinarians Need to Know?. Animals (Basel). 2021;11(3):892. Published 2021 Mar 20. doi:10.3390/ani11030892
  3. Sinn, L. Advances in behavioral psychopharmacology. Vet. Clin. North. Am. Small. Anim. Pract. 48, 457–471 (2018).
  4. Corsetti S, Borruso S, Malandrucco L, et al. Cannabis sativa L. may reduce aggressive behaviour towards humans in shelter dogs [published correction appears in Sci Rep. 2021 Dec 9;11(1):24029]. Sci Rep. 2021;11(1):2773. Published 2021 Feb 2. doi:10.1038/s41598-021-82439-2
  5. Watson KK, Bryan AD, Thayer RE, Ellingson JM, Skrzynski CJ, Hutchison KE. Cannabis Use and Resting State Functional Connectivity in the Aging Brain. Front Aging Neurosci. 2022;14:804890. Published 2022 Feb 10. doi:10.3389/fnagi.2022.804890

 

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